Osteosarcoma (OS) is the most common bone cancer in dogs. Large and giant breeds such as Irish Wolfhound, Great Dane, Greyhound, Scottish Deerhound, Rottweiler, Boxer, Saint Bernard, and Irish Setter are most affected.

Osteosarcoma is treated with a combination of surgical removal of the primary tumor and chemotherapy for metastatic disease. Surgical removal of the tumor usually involves limb amputation or limb salvage surgery, which can have high complication rates, and not all dogs are suitable for limb amputation. Even after surgical tumor removal and chemotherapy, the cancer often spreads to distant organs and dogs usually die of metastatic disease spread within an average of 12 months after diagnosis. Survival times have not greatly improved over the last 30 years.

Histotripsy is a precision non-thermal focused ultrasound method that mechanically breaks down tissues, can potentially induce immune activation towards an anti-OS immune response, and is an emerging modality for treating multiple cancers including liver and brain cancer. Histotripsy holds exciting potential to be a non-surgical option for treating the primary tumor in OS and also as a therapy that stimulates an anti-tumor immune response. This presentation aims to introduce histotripsy as a potential treatment for canine OS.

Running time: 46 mins followed by 9 mins of Q&A
This presentation is no longer eligible for CE credit

You might also like

Dispelling Cancer Treatment Myths And Addressing Quality Of Life Of Affected Dogs And Cats

12/11/2024

Cancer is a word that can evoke a lot of fear and uncertainty, especially when it affects our animal...

Read More

Supporting The Cancer Patient: Managing Cancer Pain, Nutritional Needs Of Patients, And Supporting The Caregiver Through It All

12/04/2024

Aside from the plan prescribed to treat a pet’s cancer, we have to ensure that we are addressi...

Read More

Hemangiosarcoma - What We Know And How That's Changing The Paradigm Of Treatment And Prevention

11/13/2024

Hemangiosarcoma is a malignant tumor and, historically, associated with a poor long term prognosis....

Read More

Treating Cancer - It's Not Just Limited To "chemo" Or "radiation"

11/06/2024

There are different approaches to cancer treatment and, for some types of cancer, the therapy may be...

Read More

Cancer Diagnostics - What Is Helpful? What Is Hype Or Truly Offers Hope?

10/30/2024

The mention of 'cancer' can evoke a wide range of emotions ranging from fear to concern to confusion...

Read More

The Current Thinking About What Cancer Is And Its Possible Causes

10/23/2024

Cancer is a term that is often shrouded in uncertainty and fear, but gaining a clear understanding o...

Read More